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Dentro del ciclo, la arginina es hidrolizada por la arginasa heptica (isoforma I) para producir urea y ornitina, donde la ornitina retorna al inicio del ciclo mediante el transportador mitocondrial ORC1 y la urea es eliminada por excrecin renal
Loriot, Y
10.1111/jcmm.15009 69 HensleyC
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Dose modifications guided by these findings can help reduce the risk, but this requires careful physician supervision
