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Future trials must incorporate robust biomarkerssuch as NFB activation levels, tumor suppressor gene methylation status, or immune cell cytotoxicityto identify which patients are most likely to benefit

The different types of toxicity to drugs include dose-dependent reactions that may be an extension of a drugs therapeutic effect, pathological toxicity, genotoxicity, allergic reactions, and idiosyncratic reactions (see Side Bar TYPES OF THERAPEUTIC DRUG TOXICITY)

Chen R, Ma H, Li X, Wang M, Yang Y, Wu T, Zhang Y, Kong H, Qu H, Zhao Y (2023) A novel drug with potential to treat hyperbilirubinemia and prevent liver damage induced by hyperbilirubinemia: carbon dots derived from Platycodon grandiflorum

BPC-157 is a Section S0 non-approved substance, prohibited at all times, and detectable via mass spectrometry protocols developed specifically for anti-doping testing