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Disease evolution and response to rapamycin in activated phosphoinositide 3-kinase delta syndrome: the european society for immunodeficiencies-activated phosphoinositide 3-kinase delta syndrome registry

After transporting fatty acids from the cytoplasm to the mitochondria, L-carnitine returns to the cytoplasm for the next cycle using carnitine-acylcarnitine translocase (CACT), while acetyl-CoA may enter (under aerobic conditions at low concentrations of ATP) -oxidation, with the final production of acetyl-CoA (Figure 2) [83]

doi: 10.1093/jn/nxy091, 66

M.de MarcoA
