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The BBB is composed of endothelial cells with tight junctions, pericytes, and astrocyte end-feet, all of which rely on tightly regulated lipid homeostasis to preserve barrier integrity and control permeability (Singh and Vellapandian, 2023)

The raw files were processed via MaxQuant (v2.2.0.0) against the UniProt Human database (2023_01 release), with carbamidomethylation as a fixed modification and methionine oxidation as a variable modification

The term lipotropic literally means fat-loving, referring to compounds that promote the transport, breakdown, and removal of fat from the liver

difficile both in vitro and in vivo

Some molecular species contain an additional fatty acid attached to the amide-linked 3-hydroxy acid, and the phosphate group may be substituted with ethanolamine-phosphate (of GlcN I)