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One honest caveat up front, because it shapes everything below: the evidence base for 5-Amino-1MQ is almost entirely preclinical mouse and cell-culture studies

Antineoplastic agents, corticosteroids, and so on can suppress immune function

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In proof-of-concept studies, NNMT inhibitors (NNMTis) have demonstrated promise as potential treatments for obesity and obesity-related metabolic comorbidities (e.g., T2D, fatty liver) 8,9,13
