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Leptin is an important hormone that maintains body weight by acting through a negative feedback mechanism of energy consumption and utilization

[DOI] [PMC free article] [PubMed] [Google Scholar] 232.Chini EN, Chini CCS, Espindola Netto JM, de Oliveira GC & van Schooten W The pharmacology of CD38/NADase: an emerging target in cancer and diseases of aging

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Similarly, fisetin, a flavonoid found in strawberries and other fruits, activates SIRT1 by increasing NAD + levels while also reducing oxidative stress and inflammation 179 (Fig
