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Inhibition of glutathione depletion by retinoic acid and tocopherol protects cultured neurons from staurosporine-induced oxidative stress and apoptosis

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These dietary antioxidants or anti-inflammatory nutrients may influence hearing health by regulating the expression of autophagy-related genes (e.g., LC3-II, Beclin-1) and inhibiting key proteins in apoptotic signaling pathways (e.g., caspase-3, Bax), thus preventing cell apoptosis (55)