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Understanding these distinct origins and their specific roles in the progression of radiation-induced skin fibrosis is essential to develop targeted and effective therapeutic strategies

It is known that the Lrp transcription factor reacts to excess cysteine and induces AlaE, a multifunctional transporter that pumps cysteine out of the cell until its level can be reduced

Strajhar P, Vizeli P, Patt M, et al

Amelia-Yap ZH, Sofian-Azirun M, Chen CD, Lau KW, Suana IW, Syahputra E, et al

Nat Cell Biol 17(3):288299
