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Presumably, curbing TNFa expression with GSH may inhibit MMP activities

It allows the reaction to occur in the environment in which it is present

Histones are a group of highly basic and conserved proteins located in the nucleus and are a key component of the web-like structures that are released by activated neutrophils

This creates a cascade of inflammation that affects multiple systems, leading to debilitating symptoms that often masquerade as other diseases

Subsequently, TML enters the mitochondria and interacts with the trimethyllysine hydroxylase (TMLD, encoded by the trimethyllysine hydroxylase epsilon gene: TMLHE) which converts TML into 3-hydroxy-N-trimethyllysine[24]