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These distinct roles have been associated with their heterogeneous activation profile assumed in different stages of the disease (108, 134, 135)
10.2105/ajph.2005.073213 47 ShenkJ
For four hotspots, the first hotspot is located on blades 23 of the semaphoring (SEMA) homology domain -propeller, the known HGF chain binging site
11 Biochemical Pharmacology (PubMed)Glutathione in hepatic detoxification and conjugation
The most well-characterized cytosolic GST classes have been named alpha (GSTA), mu (GSTM), pi (GSTP), and theta (GSTT)
