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Dysregulation across both systems simultaneously creates a broader picture of blunted affect

Folic acid is crucial during periods of rapid cell division and tissue growth, such as fetal development, and is therefore significant in enhancing childhood development outcomes, especially in the nervous system (, )

Appears to be well tolerated in small amounts, short-term, but its long-term safety is unknown

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More serious deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes