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Consistent with findings in P60-70 mice, WT and KI animals sustained comparable levels of attack during SDS and both displayed pronounced social avoidance following stress exposure (Additional file 1: Fig

Cardiac dysfunction Impaired cardiac energetics, increased oxygen consumption and reduced cardiac efficiency are associated with contractile dysfunction in T2D.51 Healthy hearts are able to maintain the ratio between phosphocreatine (PCr) and ATP (PCr/ATP) in response to increased workload, demonstrating metabolic flexibility

doi: 10.1021/jf9008795

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They examined protein expression of enzymes related to oxidative stress and Fe 2+