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If you are sleep deprived, you will fall asleep almost immediately after putting your head down on your pillow (short sleep latency)

Some users feel changes within days, while others notice subtle improvements over a few weeks

doi: 10.1016/S0140-6736(12)60282-7

Chem Res Toxicol 25:838849 Lobenhofer EK, Auman JT, Blackshear PE, Boorman GA, Bushel PR, Cunningham ML, Fostel JM, Gerrish K, Heinloth AN, Irwin RD, Malarkey DE, Merrick BA, Sieber SO, Tucker CJ, Ward SM, Wilson RE, Hurban P, Tennant RW, Paules RS (2008) Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype
[Google Scholar] 40.Jiao J, Fan J, Zhang Y, Chen L