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American financial institution Wells Fargo was beating the odds in a bad economy
Under pathological conditions such as calcium overload, higher ROS, ATP depletion, or ischemic injury, the mPTP can open transiently or persistently, leading to dissipation of the mitochondrial membrane potential, matrix swelling, and rupture of OMM [38,39,40,41]
Hypertension 1989
Pathogenic tau can also cause the nuclear envelope to be involute, disrupting the nucleoskeleton
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