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doi: 10.1038/nchembio.497, 38 DingL.LiX.GuoY

Functional two-way crosstalk between brain and lung: the brainlung axis

10,278 Genetic suppression of the IKK/NF-B pathway, achieved through the deletion of one p65 allele, or pharmacological intervention via IKK inhibitors, such as 8K-NBD, has been shown to delay the onset and mitigate the severity of aging symptoms and age-related pathologies in the nervous system of murine models 10,279

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The efficacy of approved ADCs in treating hematologic malignancies is significantly influenced by their ability to target immune-specific biomarkers, which are often highly expressed in malignant blood cells