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Clin Neuropharmacol 2015;38:11-7
Chronic Stress : Long term physical or emotional stress increases oxidative stress, which can deplete the bodys natural antioxidant reserves
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Collectively, oxidative stress, mitochondrial dysfunction, and glutamate excitotoxicity are causing each other forming a neurotoxic vicious cycle (80)

Borasio GD, Robberecht W, Leigh PN, et al
