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Description
PMID: 12668216 Pavlova IV et al
Domain I consists of a central four-stranded beta-sheet flanked on one side by two alpha-helices and on the other side by an irregular segment containing three short 3(10)-helices, while domain II is entirely helical
doi:10.24953/turkjped.2016.05.016
Pinealon is not FDA-approved for human use
A mutant 2 AR in which all the phosphorylation sites are altered, such that there is no agonist-induced phosphorylation, shows impaired ubiquitination as well as significantly reduced -arrestin interaction [70, 80]
