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FIGURE 3 The initiation of pyroptosis depends on the sensing of the extracellular microenvironment, primarily through TLRs (Nystrm et al., 2013) or the cytosolic space via NOD-like receptors (NLRs) (Qiu et al., 2017)

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Serle said, noting that episcleral venous pressure is the most distal resistance to trabecular outflow

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