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For instance, under both experimental and pathological conditions, vascular impairment and reduced heart function are influenced by peroxynitrite (ONOO ), a potential oxidant generated through the chemical reaction between superoxide radicals (O ) and NO, capable of producing irreversible cytotoxic effects [63, 89]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 60.Yu Z, Wolf P