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Seventy percent of study volunteers showed collagen increases compared to untreated controls a response rate significantly higher than that achieved by either comparator compound, both of which are considered first-line clinical options for photoaged skin

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GHK-Cu and Fibroblast Research Studies have shown that GHK-Cu increases messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts at nanomolar concentrations, and has also been shown to restore replicative vitality to fibroblasts following radiation damage