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(III) the activation of the enzyme gamma-glutamylcysteine synthetase that helps the futile cycle to continue without synthesizing GSH

For example, cellular senescence, classified as an antagonistic/secondary hallmark of aging, results as a consequence of persistent DNA and/or proteomic damage (primary hallmarks) that drives integrative hallmarks such as chronic inflammation and altered intracellular signaling, which further perpetuate other aging hallmarks

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Glutathione Side Effects Glutathione is a powerful antioxidant that helps support your immune system

[DOI] [PubMed] [Google Scholar] 109.Kurhaluk N., Kamiski P., Lukash O., Tkaczenko H