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Finally, one trial in 239 participants already suffering from chemotherapy-induced peripheral neuropathy reported a reduction in the severity of neuropathic symptoms with ALCAR (3 g/day for eight weeks) compared to placebo (93)

Askarpour M, Hadi A, Miraghajani M, Symonds ME, Sheikhi A, Ghaedi E

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Among them, TMAO has attracted attention recently, with evidence supporting an association between circulating levels of TMAO and increased risks of CVDs and higher all-cause mortality (8, 9)

Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice
