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Description
19, 20 The p.Asp444His variant in trans with a severe BTD pathogenic variant is associated with partial biotinidase deficiency, while in cis with p.Ala171Thr (i.e., as the double mutant p.[(Ala171Thr);(Asp444His)]), results in a profound biotinidase deficiency allele

Treating elderly subjects with brief oral supplementation with cysteine and glycine improved both the FSR and ASR of glutathione to levels observed in young humans
Distribution The distinct neuroanatomical localization of GlyT1 and GlyT2 is relevant to their respective functions in both inhibitory and excitatory signaling (Zafra et al

Daan NM, Louwers YV, Koster MP, et al

73 The trial of SAM treatment for ALD is inconclusive
