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Key manifestations of mitochondrial dysfunction include excessive mtROS accumulation, mtDNA damage and mutations, reduced ATP synthesis, and altered mitochondrial membrane potential (MMP)
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10.3390/cells11142220 23 NieberlerM.ReuningU.ReichartF.NotniJ.WesterH.-J.SchwaigerM.et al (2017)

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( M ) Metabolic protein expression of M38 316323 specific CD8 + T cells