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Parallel progression of primary tumours and metastases

After finding this site, it seems its a common occurrence
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[DOI] [PubMed] [Google Scholar] 130.Blunston M.A., Yonovitz A., Woodahl E.L., Smolensky M.H

doi: 10.1016/j.ajpath.2013.06.008

The combination reduced signal transduction more than cabozantinib alone by reducing pERK and pAKT proteins [57]