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89 YeC.LuoQ.GuoL.GaoC.XuN.ZhangL.et al (2020)

Effects of dietary carbohydrate source on growth performance, diet digestibility and liver glucose enzyme activity in blunt snout bream, Megalobrama amblycephala

The main cause seems to be contractile activity that changes the redox state in muscles to a more oxidative state, reducing the NADH/NAD ratio in mitochondria [78]

In Human, L-carnitine concentration in muscles is around 3 and 6 mol of per gram making muscle the major reservoir for L-carnitine in the body, however, it has been shown that L-carnitine present in the muscle does exchange easily with the plasma and muscle is unable to synthesize carnitine and relies on L-carnitine synthesized elsewhere in the body or from the dietary carnitine

The potential stimulating events in the dura are mast cell degranulation secondary to stress, CGRP release, and nitroglycerin infusion, which are related to vasodilatation and sudden intracranial pressure changes