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Various issues in your body affect each other
MMA, unlike homocysteine, is not influenced by folate or vitamin B6
Neuroinflammation and energy metabolism: a dual perspective on ischemic stroke

10.1177/00368504221137458 97 VenkatasubramanianA.ThiyagarajA.SubbiahV.SolairajaS.ArumugamS.RamalingamS.et al (2021)

He's also taken the herb echinacea in an attempt to prevent cold and flu, but acknowledges the evidence is a bit mixed