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The dual agonist mechanism provides robust glycemic control and significant weight reduction, with clinical trials demonstrating A1C reductions of 1.92.4% and weight loss of approximately 1522% of body weight in non-diabetic adults with obesity (SURMOUNT-1 trial), with more modest weight loss typically observed in patients with type 2 diabetes

Allergic reactions to any component are possible but uncommon

For women, this means having no more than 1,400 calories a day or 1,900 calories for men

In the mice with A1Rs that were fed the KD, seizures were nearly abolished after four weeks of treatment