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11 However, their place in therapy remains to be fully elucidated

Furthermore, a translational study in domestic cats showed that combining CAP with a multimodal pharmacologic regimen (ketamine, gabapentin, amitriptyline, and prednisone) led to significant improvement in both chronically infected skin lesions and postsurgical neuropathic pain [465]

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The extract of pruriens free of LDs contained catechols and polyphenols, which upregulated the expression of NO-producing genes