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10.31486/toj.18.0076 38 GoodmanS

By measuring mitochondrial ROS levels and PRDX6 protein and mRNA expression, it has been found that Si Jun Zi Tang can lower ROS levels and PRDX6 expression, inhibiting ferroptosis in colonic tissue macrophages, thereby improving DSS-induced mouse UC ( The Li Zhong decoction (LZD), originating from the Shang Han Lun, is composed of Renshen ( P

D 2 : dopamine receptor type 2

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All these three substances have been tested in animal models showing protective effects on kidneys and intestine and heart
