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The study addresses the gap in understanding the redox characteristics of MLOs, which are critical for concentrating specific proteins and nucleic acids without a lipid membrane

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Interestingly, in the context of the transgenic mice expressing the mutant human B-crystallin, heterozygous knockout of Nrf2 lessened reductive stress decreasing the expression of the enzymes involved in GSH biosynthesis and recycling, resulting in a decrease in GSH concentration and the GSH/GSSG ratio

P., Pinzon, R

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