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J Immunol, 2006

Additionally, among SASP factors, there are growth factors such as vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and insulin-like growth factor 1 (IGF-1), which, when secreted into the environment by senescence cells, stimulate the repair and regeneration of surrounding tissues [13]

Weakness or numbness in the face, mouth, and neck may be associated with a tumor or other structural abnormality pressing on a nerve

The danger model was first suggested in 1994, were it was first postulated that the immune system responds to substances that cause damage, rather than to those that are simply foreign (93, 94)

22 - 25 Background of the Roberts concept (stomach cytoprotection and organoprotection) versus the Selyes concept (stress coping response) Roberts stomach cytoprotection 14 - 19 and organoprotection 20 , 21 and the Selyes stress coping response 22 - 25 both intend to reestablish homeostasis