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This article covers the actual week-by-week progression for different skin types, what affects melanin response rates, and why maintenance dosing looks completely different from the loading phase

An alternative etiology for the initial pigmentation is smokers melanosis, a condition observed in approximately 2531% of tobacco users [8]

Front Cell Dev Biol (2021) 9:702508
Limb-sparing surgery is often preferred when feasible, but amputation may be considered for tumors that extensively involve critical structures

Journal of Clinical Endocrinology & Metabolism (2024) 7