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While testosterone primarily increases muscle protein synthesis and reduces fat through androgen receptor activation, GH promotes lipolysis and collagen synthesis through separate pathways (Gibney et al., 2005)

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FIGURE 6 3.6 GHK-Cu promoted mucosal healing via inhibiting STAT3 activation To investigate the role of STAT3 activation in facilitating the therapeutic benefits of GHK-Cu, we meticulously designed and executed STAT3 knockdown experiments in vitro , utilizing the co-culture model