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Description
Experimental neurobiology
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That belief shaped clinical decisions, scared men away from treatment, and - as it turns out - was built on a far shakier scientific foundation than most people realized
doi: 10.1083/jcb.202210078 55 RussellRCTianYYuanHParkHWChangY-YKimJet al
Here, for the first time, our work clarified the detailed mechanism on how TRPM7 participates in pyroptosis and epileptogenesis, and how targeting TRPM7 may pave the way for a new generation of drugs to treat SE and other neurological conditions, among which neuronal pyroptosis is a hallmark pathology
