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For instance, high levels of UPF consumption have been found to be associated with an increased odds of developing ASD in adolescents, while experimental studies indicate that acrylamide, which is a compound frequently present in UPFs, may, in some cases, induce autism-like behaviors as a result of a number of important pathophysiological mechanisms that result in neuroinflammatory changes as well as oxidative stress (151, 160)

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Lipidomic analysis of hepatocytes with different ApoE genotypes revealed that ApoE 4 may promote systemic metabolic imbalance by interfering with lipid distribution, glucose metabolism, and adipose tissue inflammation [84]

In Huntingtons disease, glutamate and GABA concentrations decrease in striatum and caudate nucleus from brain [60,70]

The FDA has issued advisories against using it for unproven cosmetic benefits like skin lightening 2
