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grant number 19PABH134580006 from the AHA/Allen Initiative in Brain Health and Cognitive Impairment team

doi: 10.1159/000486135

If you have numbness, tingling, balance problems, or memory changes, see a clinician promptly, because neurological damage from vitamin B12 deficiency can become permanent when treatment is delayed

Conversely, the inhibition of the de novo synthesis of GSH dampens intracellular antioxidant defence mediated by this system and increases oxidative stress (Reference Lian, Gnanaprakasam and Wang28)

However, genetic variationsknown as SNPs (Single Nucleotide Polymorphisms)can disrupt this delicate balance, increasing susceptibility to chronic conditions, mental health challenges, and detoxification issues