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Dehydrated skin tends to be less elastic and more prone to irritation, which can hinder the effectiveness of the treatment

It is ideal for research focused on metabolic rate, substrate utilization, and mild-to-moderate obesity

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Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB (2014) Nicotinamide N -methyltransferase knockdown protects against diet-induced obesity