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Description
However, targeting HO-1 at any stage may compromise its antioxidant function

The next step after this would be the validation of the identified hub proteins by conducting further in vitro as well as in vivo studies

Patients who dont convert T4 to T3 well do better on bio-identical hormones like Armour, because it contains both T4 and T3 (in a 4.22:1 ratio)
One carbon pathways were disrupted

doi:10.1016/j.bone.2005.04.017
