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PMID: 35710796 Autophagy XIAP-ULK1-Mediated mitophagy modulates carnitine metabolism to mitigate diabetic kidney disease

aka Toxicology Conundrum 056 This case-based Q&A follows on from Toxicology Conundrum 055, lets recap: A 35 year-old male is brought in by ambulance after being discovered by friends in a semi-comatose state and surrounded by empty pill packets

10.2217/fon-2018-0207 Future Oncol

Huertas R, Campos Y, Daz E, Esteban J, Vechietti L, Montanari G, D'Iddio S, Corsi M, Arenas J: Respiratory chain enzymes in muscle of endurance athletes: effect of L-carnitine

200 A randomized placebo-controlled trial involving 75 subjects with fibromyalgia found 100 mg of oral magnesium (as magnesium chloride) once daily for one month improved scores on the Depression Anxiety Stress Scale and reduced pain severity in a subgroup of participants with mild-to-moderate stress, but had no effect on symptom parameters in those with severe-to-extremely severe stress