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Furthermore, a vitamin B12 deficiency is also known to cause dark circles

Pain-related outcomes such as burning sensation, and spontaneous pain were all significantly reduced in both groups at the 12-week endpoint of the study

Second, vitamin B12 supports methylation and cellular metabolism, including the conversion of homocysteine and the handling of methylmalonic acid

Aleknaviciute G, et al

PMID 20445536.
