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Reportedly, serum and urine levels of citrulline, ornithine, threonine, and methionine were found decrease substantially following both single (10 mg/kg, i.p.) and escalating (10, 12.5, 15, 20, and 30 mg/kg, i.p.) administration of MA, returning to baseline levels after a 2-day withdrawal period in Sprague Dawley rats 49

J Androl 21 : 8590 Riedl CR et al

TBI pathology involves primary injury which induces secondary injury pathways

The brainstem, which has been implicated to be affected in PASC, explaining the broad spectrum of symptoms, particularly pain and autonomic symptoms [156], has been found to show glucose hypometabolism in patients (among other regions) [47, 53, 89]

Cell 25 (1), 233240