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Furthermore, A-KG can be further metabolized to 2-hydroxyglutarate, inducing mitochondrial ROS accumulation and activating the p53 pathway, collectively promoting ferroptosis (51)

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5 However, the use of medicinal plants with antioxidant properties has been explored for their ability to treat or prevent several human pathologies, with oxidative stress being one of the underlying causes

Similar content being viewed by others Introduction Lifestyle and eating habits have changed significantly over the years, driven by shifts from traditional whole foods to a higher consumption of processed foods, increased convenience and snacking, along with the influence of technological advancements and globalization on food availability and consumption patterns [1,2,3]