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To evaluate the factors that contribute to the age-related decline in skeletal muscle regeneration in a more comprehensive manner, we have generated single-cell RNA-sequencing (scRNA-seq) datasets of uninjured (day 0) and myotoxin-injured (days 1, 2, 3.5, 5 and 7) tibialis anterior (TA) muscles from young, old and geriatric mice

This aspect of ease of administration enhances the overall treatment experience, making it simpler and more reliable for patients to integrate into their health routines

We found that the old and geriatric T cells have a higher T cell exhaustion score compared to the young (Fig

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However, patient experience is mixed: while some members report no difference between the two methods, others find they do not achieve the same symptom resolution with SC injections