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TP53 germline variations influence the predisposition and prognosis of B-cell acute lymphoblastic leukemia in children

A novel kinase inhibitor, INCB28060, blocks c-MET-dependent signaling, neoplastic activities, and cross-talk with EGFR and HER-3

.,LeeAPoonMCInherited platelet functional disorders: General principles and practical aspects of management.2018;57:494501

Yes its mechanism (circadian and telomerase-related signalling) is not sex-hormone dependent, unlike therapies tied to the HPG axis
S., Saidu Y., Nasiru J
