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A., Rmer, J., Ahnfelt-Rnne, I., Ohlsson, C., & Jansson, J

PGE2, prostaglandin E2

Notably, lung cancer cells with KEAP1 mutations exhibit Nrf2 activation and sensitivity to GLS inhibition [37], suggesting that the use of GLS inhibitors has a good prospect in the treatment of lung cancer patients with KEAP1 mutations, and may provide a new therapeutic strategy for the treatment of patients with high SLC7A11 expression in their lung tumors

134 Lao CD, Ruffin MT, Normolle D, Heath DD, Murray SI, Bailey JM, Boggs ME, Crowell J, Rock CL, Brenner DE (2006) Dose escalation of a Curcuminoid formulation

Of late, multiple transcription factors such as TFAP2C, p53, AP-1, STAT, Nrf2, HIF-1, and C/EBP have been linked with the transcriptional regulation of seleno-GPxs [8, 21,22,23,24]