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Catalytic activity and physiological roles of CD38 As discussed above, CD38 is a multifunctional enzyme that uses -NAD and other -NAD derivatives, such as -NADP and -NMN, as substrates

Nat Genet (2004) 36(9):10037.10.1038/ng1406 68 BroerS

Furthermore, they are able to activate biochemical defense pathways of plants
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Pulmonary epithelium, cigarette smoke, and chronic obstructive pulmonary disease