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During the process of maturation, B cells may develop into autoreactive B cells, characterized by their undesired expansion and activation, which can potentially trigger SLE (54)

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Moreover, epigenetic modifications, including redox-sensitive DNA methylation and histone acetylation, may play a pivotal role in sustaining maladaptive tendon remodeling (Sakai and Kumagai, 2025

Suter PM, Domenighetti G, Schaller MD, et al
