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All activities involving the reagent must be carried out by qualified personnel under laboratory conditions, in accordance with the applicable regulations
There is a theoretical --- though as yet unproven in humans --- risk that long-term or high-dose use could stimulate growth in existing malignant or pre-malignant cells
(2021) used polycaprolactone material as a mechanical support framework, loaded with CTGF or TGF-3 polydopamine nanoparticles and mixed with mesenchymal stem cells (BMSCs) to promote nucleus pulposus and annulus fibrosus cell regeneration
