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Studies show "increased energy and slight weight changes within the first few weeks" with more substantial changes following

For instance, the robust association we report between low prenatal vitamin D and increased ASD risk is consistent with earlier prospective studies in diverse populations [19]

This is because after this period, the bacteriostatic preservative can no longer prevent contamination, often leading to a compromised product that can put the patients at risk

2011 Mar;110(3):774-80
2005 Aug;186(2):273-89